The EAWAG-BBD Phenylacetate Pathway

• 2-oxepin-2(3H)-ylideneacetyl-CoA -----> 3-Oxo-5,6-dehydrosuberyl-CoA (reacID# r1732)
• 1,2-Epoxyphenylacetyl-CoA -----> 2-oxepin-2(3H)-ylideneacetyl-CoA (reacID# r1731)
• Fumarylacetoacetate -----> Acetoacetate + Fumarate (reacID# r0107)
• Homogentisate -----> 4-Maleylacetoacetate (reacID# r0105)
• 2-Hydroxyphenylacetate -----> Homogentisate (reacID# r0252)
• 4-Maleylacetoacetate -----> Fumarylacetoacetate (reacID# r0106)
• 3-Oxo-5,6-dehydrosuberyl-CoA -----> Acetyl-CoA + 5-Carboxy-2-pentenoyl-CoA (reacID# r1733)
• Phenylacetate -----> 2-Hydroxyphenylacetate (reacID# r0036)
• Phenylacetate -----> Phenylacetyl-CoA (reacID# r1729)
• Phenylacetyl-CoA -----> 1,2-Epoxyphenylacetyl-CoA (reacID# r1730)

• Acetoacetate [541-50-4] (compID# c0069)
• Acetyl-CoA [72-89-9] (compID# c0031)
• 5-Carboxy-2-pentenoyl-CoA (compID# c0943)
• 2-oxepin-2(3H)-ylideneacetyl-CoA (compID# c1496)
• 1,2-Epoxyphenylacetyl-CoA (compID# c1495)
• Fumarate [110-17-8] (compID# c0111)
• Fumarylacetoacetate [28613-33-4] (compID# c0110)
• Homogentisate [451-13-8] (compID# c0108)
• 2-Hydroxyphenylacetate [614-75-5] (compID# c0223)
• 4-Maleylacetoacetate [5698-52-2] (compID# c0109)
• 3-Oxo-5,6-dehydrosuberyl-CoA (compID# c1497)
• Phenylacetate [103-82-2] (compID# c0211)
• Phenylacetyl-CoA (compID# c1494)

• EC 1.13.11.5 homogentisate 1,2-dioxygenase (enzymeID# e0081)
• EC 1.14.13.- 2-hydroxyphenylacetate hydroxylase (enzymeID# e0198)
• EC 1.14.13.149 phenylacetyl-CoA 1,2-epoxidase (enzymeID# e1160)
• EC 1.14.14.- phenylacetate hydroxylase (enzymeID# e0197)
• EC 2.3.1.16 acetyl-CoA C-acyltransferase (enzymeID# e0653)
• EC 3.7.1.2 fumarylacetoacetase (enzymeID# e0083)
• EC 3.7.1.16 oxepin-CoA hydrolase (enzymeID# e1162)
• EC 5.2.1.2 maleylacetoacetate isomerase (enzymeID# e0082)
• EC 5.3.3.18 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (enzymeID# e1161)
• EC 6.2.1.30 phenylacetate--CoA ligase (enzymeID# e1159)

Page Author(s): Lynda Ellis and Shawn Balcome
Tue May 31 10:45:52 CDT 2011 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Phenylacetate Pathway.
It was generated on March 12, 2025 at 8:46:00 PM CDT.

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