From 3-Oxo-5,6-dehydrosuberyl-CoA to Acetyl-CoA and 5-Carboxy-2-pentenoyl-CoA

Graphic of the reaction.
Medline reference: Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G. Proc Natl Acad Sci U S A (2010) 107(32): 14390-5.
Search Medline titles for bacterial phenylacetate metabolism.: 18 citations on September 27, 2012.

       3-Oxo-5,6-dehydrosuberyl-CoA        
                     |
                     |  CoASH
          acetyl-CoA | /
   C-acyltransferase |/
            2.3.1.16 | Search GenBank, 831 hits on Apr. 03, 2012
               Kyoto |
              ExPASy |
                     |
                     v
  Acetyl-CoA + 5-Carboxy-2-pentenoyl-CoA

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: 3-Ketoacetyl-CoA derivative -----> CoA thioester + Acetyl-CoA (bt0161)

[Phenylacetate] [BBD Main Menu]

Page Author(s): Lynda Ellis and Shawn Balcome
May 31, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1733.
It was generated on November 11, 2025 at 4:53:05 PM CST.

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