From 2-oxepin-2(3H)-ylideneacetyl-CoA to 3-Oxo-5,6-dehydrosuberyl-CoA

Graphic of the reaction.

Medline reference
Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G. Proc Natl Acad Sci U S A (2010) 107(32): 14390-5.

Search Medline titles for bacterial phenylacetate metabolism.
18 citations on September 27, 2012. 
  2-oxepin-2(3H)-ylideneacetyl-CoA   
                  |
                  |  2H2O + NADP+
       oxepin-CoA | /
        hydrolase |/
         3.7.1.16 |
            Kyoto |\
           ExPASy | \
                  |  NADPH + H+
                  v
    3-Oxo-5,6-dehydrosuberyl-CoA
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Enol ether -----> Keto + Alcohol (bt0158)
[Phenylacetate] [BBD Main Menu]

Page Author(s): Lynda Ellis and Shawn Balcome
May 31, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1732.
It was generated on March 11, 2026 at 5:05:50 AM CDT. 

© 2026, EAWAG.