The EAWAG-BBD 2,4-Dichlorophenoxyacetic Acid Pathway

• cis-4-Carboxymethylenebut-2-en-4-olide -----> Maleylacetate (reacID# r0286)
• 5-Chloro-2-hydroxymuconate -----> 5-Chloro-2-oxopent-4-enoate (reacID# r1435)
• 5-Chloro-2-hydroxymuconic semialdehyde -----> 5-Chloro-2-hydroxymuconate (reacID# r1434)
• 5-Chloro-2-hydroxymuconic semialdehyde -----> 5-Chloro-2-oxopent-4-enoate (reacID# r0289)
• 5-Chloro-2-oxopent-4-enoate -----> 5-Chloro-4-hydroxy-2-oxopentanate (reacID# r1436)
• 5-Chloro-4-hydroxy-2-oxopentanate -----> Chloroacetaldehyde + Pyruvate (reacID# r1437)
• 3-Chloro-cis,cis-muconate -----> cis-4-Carboxymethylenebut-2-en-4-olide (reacID# r0285)
• 3-Chloro-cis,cis-muconate -----> 4-Methylenebut-2-en-4-olide (reacID# r0284)
• 4-Chlorocatechol -----> 5-Chloro-2-hydroxymuconic semialdehyde (reacID# r0287)
• 4-Chlorocatechol -----> 3-Chloro-cis,cis-muconate (reacID# r0283)
• cis-2-Chlorodienelactone -----> 2-Chloromaleylacetate (reacID# r0279)
• trans-2-Chlorodienelactone -----> cis-2-Chlorodienelactone (reacID# r0278)
• 2-Chloromaleylacetate -----> Maleylacetate (reacID# r0098)
• 4-Chlorophenol -----> 4-Chlorocatechol (reacID# r0282)
• 4-Chlorophenoxyacetate -----> 4-Chlorophenol + Glyoxylate (reacID# r0281)
• 2,4-Dichloro-cis,cis-muconate -----> trans-2-Chlorodienelactone (reacID# r0277)
• 3,5-Dichlorocatechol -----> 2,4-Dichloro-cis,cis-muconate (reacID# r0276)
• 2,4-Dichlorophenol -----> 3,5-Dichlorocatechol (reacID# r0275)
• 2,4-Dichlorophenoxyacetic acid -----> 4-Chlorophenoxyacetate (reacID# r0280)
• 2,4-Dichlorophenoxyacetic acid -----> 2,4-Dichlorophenol + Glyoxylate (reacID# r0274)
• Maleylacetate -----> 3-Oxoadipate (reacID# r0099)
• 4-Methylenebut-2-en-4-olide -----> cis-Acetylacrylate (reacID# r0404)

• cis-Acetylacrylate [4743-82-2] (compID# c0386)
• cis-4-Carboxymethylenebut-2-en-4-olide [3374-46-7] (compID# c0299)
• 5-Chloro-2-hydroxymuconate (compID# c1246)
• 5-Chloro-2-hydroxymuconic semialdehyde (compID# c0300)
• 5-Chloro-2-oxopent-4-enoate (compID# c1247)
• 5-Chloro-4-hydroxy-2-oxopentanate (compID# c1248)
• 3-Chloro-cis,cis-muconate [22752-96-1] (compID# c0297)
• Chloroacetaldehyde [107-20-0] (compID# c0003)
• 4-Chlorocatechol [2138-22-9] (compID# c0296)
• cis-2-Chlorodienelactone [115793-61-8] (compID# c0293)
• trans-2-Chlorodienelactone [22752-93-8] (compID# c0291)
• 2-Chloromaleylacetate [24759-04-4] (compID# c0098)
• 4-Chlorophenol [106-48-9] (compID# c0295)
• 4-Chlorophenoxyacetate [122-88-3] (compID# c0294)
• 2,4-Dichloro-cis,cis-muconate [72945-11-0] (compID# c0292)
• 3,5-Dichlorocatechol [13673-92-2] (compID# c0290)
• 2,4-Dichlorophenol [120-83-2] (compID# c0289)
• 2,4-Dichlorophenoxyacetic acid [94-75-7] (compID# c0288)
• Glyoxylate [298-12-4] (compID# c0014)
• Maleylacetate [24740-88-3] (compID# c0099)
• 4-Methylenebut-2-en-4-olide [108-28-1] (compID# c0298)
• 3-Oxoadipate [689-31-6] (compID# c0100)
• Pyruvate [127-17-3] (compID# c0159)

• EC 1.2.1.32 2-hydroxymuconic semialdehyde dehydrogenase (enzymeID# e0904)
• EC 1.3.1.32 maleylacetate reductase (enzymeID# e0063)
• EC 1.13.11.- 3,5-dichlorocatechol 1,2-dioxygenase (enzymeID# e0231)
• EC 1.13.11.1 catechol 1,2-dioxygenase (enzymeID# e0064)
• EC 1.13.11.2 catechol 2,3-dioxygenase (enzymeID# e0156)
• EC 1.14.-.- 4-chlorophenoxyacetate monooxygenase (enzymeID# e0234)
• EC 1.14.11.- 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase (enzymeID# e0230)
• EC 1.14.13.20 2,4-dichlorophenol hydroxylase (enzymeID# e0152)
• EC 1.97.1.- 2,4-dichlorophenoxyacetate reductive dehalogenase (enzymeID# e0233)
• EC 3.1.1.45 dienelactone hydrolase (enzymeID# e0066)
• EC 3.7.1.9 2-hydroxymuconate semialdehyde hydrolase (enzymeID# e0139)
• EC 4.1.1.77 4-oxalocrotonate decarboxylase (enzymeID# e0905)
• EC 4.1.3.- 5-Chloro-4-hydroxy-2-oxopentanate aldolase (enzymeID# e0907)
• EC 4.2.1.- 5-Chloro-2-oxopent-4-enoate hydratase (enzymeID# e0906)
• EC 5.2.1.- 2-chlorodienlactone isomerase (enzymeID# e0232)
• EC 5.5.1.1 muconate cycloisomerase (enzymeID# e0133)
• EC 5.5.1.7 chloromuconate cycloisomerase (enzymeID# e0065)
• EC 5.5.1.11 dichloromuconate cycloisomerase (enzymeID# e0132)

Page Author(s): Brian Hill, Eva Young, Dong Jun Oh, Rafael Blasco, Lynda Ellis and Michael Turnbull
December 15, 1997 4:44:36 PM CST Contact Us

This is the EAWAG-BBD compounds and reactions page for the 2,4-Dichlorophenoxyacetic Acid Pathway.
It was generated on April 26, 2025 at 4:50:01 PM CDT.

© 2025, EAWAG.