From 3-Chloro-cis,cis-muconate to cis-4-Carboxymethylenebut-2-en-4-olide

Graphic of the reaction.
Medline reference: Hammer A, Hildenbrand T, Hoier H, Ngai KL, Schlomann M, Stezowski JJ. J Mol Biol (1993) 232(1): 305-7.
Search Medline for chloromuconate cycloisomerase.: 36 citations on March 09, 2012.

         3-Chloro-cis,cis-muconate         
                     |
                     |
      chloromuconate |
      cycloisomerase |
             5.5.1.7 | Search GenBank, 227 hits on Apr. 03, 2012
               Kyoto |\
              ExPASy | \
                     |  Cl^-
                     v
  cis-4-Carboxymethylenebut-2-en-4-olide

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: 3-Halo-cis,cis-muconate derivative -----> cis-4-Carboxymethylenebut-2-en-4-olide derivative (bt0206)

[2,4-Dichlorophenoxyacetic Acid] [BBD Main Menu]

Page Author(s): Brian Hill
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0285.
It was generated on November 11, 2025 at 3:58:52 AM CST.

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