From 2,4-Dichlorophenoxyacetic acid to 2,4-Dichlorophenol and Glyoxylate

Graphic of the reaction.

Medline reference
Fukumori F, Hausinger RP. J Biol Chem (1993) 268(32): 24311-7.

Search Medline for 2,4-dichlorophenoxyacetate dioxygenase.
20 citations on June 22, 2012. 
                                  2,4-Dichlorophenoxyacetic acid                                   
                                                 |
                                                 |  O2 + 2-oxoglutarate
  2,4-dichlorophenoxyacetate alpha-ketoglutarate | /
                                     dioxygenase |/
                                       1.14.11.- | Search GenBank, 3 hits on Apr. 03, 2012
                                                 |\
                                          ExPASy | \
                                                 |  H2O + H+ + CO2 + succinate
                                                 v
                                  2,4-Dichlorophenol + Glyoxylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
aromatic-aliphatic Ether -----> Phenol derivative + Aldehyde (bt0023)
[2,4-Dichlorophenoxyacetic Acid] [BBD Main Menu]

Page Author(s): Brian Hill
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0274.
It was generated on November 21, 2024 at 11:12:40 AM CST. 

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