The EAWAG-BBD Styrene Pathway

• Homogentisate -----> 4-Maleylacetoacetate (reacID# r0105)
• 4-Hydroxy-2-oxovalerate -----> Pyruvate + Acetaldehyde (reacID# r0100)
• (2E,4Z)-2-Hydroxy-6-oxoocta-2,4,7-trienoate -----> Acrylate + cis-2-Hydroxypenta-2,4-dienoate (reacID# r0259)
• cis-2-Hydroxypenta-2,4-dienoate -----> 4-Hydroxy-2-oxovalerate (reacID# r0101)
• 2-Hydroxyphenylacetate -----> Homogentisate (reacID# r0252)
• 4-Maleylacetoacetate -----> Fumarylacetoacetate (reacID# r0106)
• Phenylacetaldehyde -----> Phenylacetate (reacID# r0035)
• Phenylacetate -----> 2-Hydroxyphenylacetate (reacID# r0036)
• Styrene -----> Styrene cis-glycol (reacID# r0256)
• Styrene -----> Styrene oxide (reacID# r0225)
• Styrene cis-glycol -----> 3-Vinylcatechol (reacID# r0257)
• Styrene oxide -----> Phenylacetaldehyde (reacID# r0034)
• 3-Vinylcatechol -----> (2E,4Z)-2-Hydroxy-6-oxoocta-2,4,7-trienoate (reacID# r0258)

• Acetaldehyde [75-07-0] (compID# c0160)
• Acrylate [79-10-7] (compID# c0113)
• Fumarylacetoacetate [28613-33-4] (compID# c0110)
• Homogentisate [451-13-8] (compID# c0108)
• 4-Hydroxy-2-oxovalerate [3318-73-8] (compID# c0101)
• (2E,4Z)-2-Hydroxy-6-oxoocta-2,4,7-trienoate (compID# c0226)
• cis-2-Hydroxypenta-2,4-dienoate [159694-16-3] (compID# c0102)
• 2-Hydroxyphenylacetate [614-75-5] (compID# c0223)
• 4-Maleylacetoacetate [5698-52-2] (compID# c0109)
• Phenylacetaldehyde [122-78-1] (compID# c0210)
• Phenylacetate [103-82-2] (compID# c0211)
• Pyruvate [127-17-3] (compID# c0159)
• Styrene [100-42-5] (compID# c0115)
• Styrene cis-glycol (compID# c0224)
• Styrene oxide [96-09-3] (compID# c0037)
• 3-Vinylcatechol (compID# c0225)

• EC 1.2.1.39 phenylacetaldehyde dehydrogenase (enzymeID# e0119)
• EC 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase (enzymeID# e0060)
• EC 1.13.11.2 catechol 2,3-dioxygenase (enzymeID# e0156)
• EC 1.13.11.5 homogentisate 1,2-dioxygenase (enzymeID# e0081)
• EC 1.14.12.- styrene dioxygenase (enzymeID# e0200)
• EC 1.14.13.- 2-hydroxyphenylacetate hydroxylase (enzymeID# e0198)
• EC 1.14.13.- styrene monooxygenase (enzymeID# e0195)
• EC 1.14.14.- phenylacetate hydroxylase (enzymeID# e0197)
• EC 3.7.1.9 2-hydroxymuconate semialdehyde hydrolase (enzymeID# e0139)
• EC 4.1.3.39 4-hydroxy-2-oxovalerate aldolase (enzymeID# e0077)
• EC 4.2.1.80 2-oxopent-4-enoate hydratase (enzymeID# e0078)
• EC 5.2.1.2 maleylacetoacetate isomerase (enzymeID# e0082)
• EC 5.3.99.7 styrene oxide isomerase (enzymeID# e0196)

Page Author(s): Dean Kraus, Kenneth E. Lind, Andrea Marconi and Ryan McLeish
December 15, 1997 5:00:50 PM CST Contact Us

This is the EAWAG-BBD compounds and reactions page for the Styrene Pathway.
It was generated on April 1, 2025 at 11:25:04 AM CDT.

© 2025, EAWAG.