From (2E,4Z)-2-Hydroxy-6-oxoocta-2,4,7-trienoate to cis-2-Hydroxypenta-2,4-dienoate and Acrylate

Graphic of the reaction.

Medline reference
Warhurst AM, Clarke KF, Hill RA, Holt RA, Fewson CA. Appl Environ Microbiol (1994) 60(4): 1137-45.

Search Medline for 2-hydroxymuconic semialdehyde hydrolase.
16 citations on June 22, 2012. 
            (2E,4Z)-2-Hydroxy-6-oxoocta-2,4,7-trienoate            
                                 |
                                 |  H2O
  2-hydroxymuconate semialdehyde | /
                       hydrolase |/
                         3.7.1.9 | Search GenBank, 101 hits on Apr. 03, 2012
                           Kyoto |\
                          ExPASy | \
                                 |  H+
                                 v
            cis-2-Hydroxypenta-2,4-dienoate + Acrylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)
[Styrene] [BBD Main Menu]

Page Author(s): Kenneth E. Lind and Ryan McLeish
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0259.
It was generated on April 19, 2026 at 6:01:35 AM CDT. 

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