From 4,6-Dioxoheptanoate to Succinate and Acetone

Graphic of the reaction.

Medline reference
Bartholomew BA, Smith MJ, Trudgill PW, Hopper DJ. Appl Environ Microbiol (1996) 62(9): 3245-50.

Search Medline for bacterial atropine metabolism.
21 citations on March 09, 2012. 
             4,6-Dioxoheptanoate             
                      |
                      |  H2O
  4,6-dioxoheptanoate | /
            hydrolase |/
              3.7.1.- |
                      |
               ExPASy |
                      |
                      v
             Succinate + Acetone
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1,3-Diketone -----> Ketone + Carboxylate (bt0373)
[Atropine] [BBD Main Menu]

Page Author(s): Lynda Ellis and Shawn Balcome
July 26, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1744.
It was generated on November 14, 2025 at 3:09:17 PM CST. 

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