From 1,4-Dioxane to Dioxanone

Graphic of the reaction.

Medline reference
Mahendra S, Petzold CJ, Baidoo EE, Keasling JD, Alvarez-Cohen L. Environ Sci Technol (2007) 41(21): 7330-6.

Search Medline titles for 1,4-Dioxane AND bacteria.
19 citations on September 14, 2012. 
           1,4-Dioxane           
                |
                |  O2 +2H+ + 2e-
    1,4-dioxane | /
  monooxygenase |/
      1.14.13.- |
                |\
         ExPASy | \
                |  H2O
                v
     [2-Hydroxy-1,4-dioxane]     
                |
                |
                |
                |
                |\
                | \
                |  2H+ + 2e-
                v
            Dioxanone
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2-unsubstituted Cyclic ether -----> 2-Hydroxy cyclic ether (bt0073)
secondary Alcohol -----> Ketone (bt0002)
[1,4-Dioxane] [BBD Main Menu]

Page Author(s): Eric Stevenson
April 19, 2009 Contact Us

This is the EAWAG-BBD reaction, reacID# r1571.
It was generated on November 14, 2025 at 3:03:15 AM CST. 

© 2025, EAWAG.