Rule bt0073

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Pattern 3591
2-unsubstituted Cyclic ether -> 2-Hydroxy cyclic ether

Aerobic Likelihood:              Neutral

EAWAG-BBD Reaction(s):
1,4-Dioxane -----> Dioxanone (reacID# r1571)
Endosulfan ether -----> Endosulfan hydroxyether (reacID# r1413)
Tetrahydrofuran -----> 2-Hydroxytetrahydrofuran (reacID# r0017)

If both carbon atoms adjacent to the ether oxygen are unsubstituted, hydroxylation will occur on the carbon with the most positive charge. This rule will produce cis products in rings with double bonds and is blocked from acting on epoxides.

bt0242: secondary Aliphatic --> secondary Alcohol

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Page Author(s): Bo Kyeng Hou, Michael Turnbull and Jiun-guo Yu
March 12, 2009

This is the EAWAG-BBD biotransformation rule, ruleID# bt0073.
It was generated on July 17, 2024 10:18:22 AM CDT.

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