Rule bt0242

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Pattern 3803        All patterns
secondary Aliphatic -> secondary Alcohol


Aerobic Likelihood:              Neutral

EAWAG-BBD Reaction(s):
Acenaphthalene -----> 1-Acenaphthalenol (reacID# r1822)
1-Acenaphthalenol -----> 1,2-Dihydro-1,2-acenaphthylenediol (reacID# r1824)
1,5-Anhydro-D-mannitol -----> D-Mannose (reacID# r1787)
Bisphenol F -----> Bis(4-hydroxyphenyl) methanol (reacID# r1480)
bis(4'-Chlorophenyl)acetate (DDA) -----> 4,4'-Dichlorobenzophenone (DBP) (reacID# r0517)
Cyclohexane -----> Cyclohexanol (reacID# r1059)
Ethylbenzene -----> (S)-1-Phenylethanol (reacID# r0234)
Ethylbenzene -----> (S)-1-Phenylethanol (reacID# r0249)
Fluorene -----> 9-Fluorenol (reacID# r0407)
Fluorene -----> 9-Fluorenol (reacID# r0662)
1-Ketoacenaphthalene -----> 1-Hydroxy-2-ketoacenaphthene (reacID# r1825)
Tetralin -----> (R)-1,2,3,4-Tetrahydronaphthol (reacID# r1175)

Comments:
This rule handles the hydroxylation of secondary aliphatic carbon atoms that are in a ring, adjacent to a carbon that is sp2 hybridized, or bound to N or O. Esters and amides are blocked from triggering this rule.

Similarities:
bt0073: 2-unsubstituted Cyclic ether --> 2-Hydroxy cyclic ether
bt0267: (+)-Camphor derivative --> 5-exo-Hydroxycamphor derivative

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Page Author(s): Bo Kyeng Hou, Michael Turnbull and Jiun-guo Yu
February 21, 2011

This is the EAWAG-BBD biotransformation rule, ruleID# bt0242.
It was generated on September 25, 2017 4:37:15 AM CDT.

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