From Isophthalate to 4-Hydro-3,4-dihydroxyisophthalate

Graphic of the reaction.

Medline reference
Vamsee-Krishna C, Mohan Y, Phale PS. Appl Microbiol Biotechnol (2006) 72(6): 1263-9.

Search Medline for Dimethyl isophthalate biodegradation.
12 citations on March 09, 2012. 
             Isophthalate             
                   |
                   |  O2 + NADH + H+
      isophthalate | /
   3,4-dioxygenase |/
         1.14.12.- |
                   |\
            ExPASy | \
                   |  NAD+
                   v
  4-Hydro-3,4-dihydroxyisophthalate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-carboxy-2-unsubstituted Aromatic -----> 1-Carboxy-1,2-dihydroxy-2-hydroaromatic (bt0368)
[Dimethylisophthalate] [BBD Main Menu]

Page Author(s): Jason Vevea
April 21, 2008 Contact Us

This is the EAWAG-BBD reaction, reacID# r1486.
It was generated on January 24, 2026 3:36:16 AM CST. 

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