From 6-Hydroxy-3-succinoylpyridine to Succinic semialdehyde and 2,5-Dihydroxypyridine

Graphic of the reaction.

Medline reference
Wang SN, Liu Z, Tang HZ, Meng J, Xu P. Microbiology (2007) 153(Pt 5): 1556-65.

Search Medline for 6-hydroxy-3-succinoylpyridine.
3 citations on March 09, 2012. 
                  6-Hydroxy-3-succinoylpyridine                  
                                |
                                |  H2O
  6-hydroxy-3-succinoylpyridine | /
                      hydrolase |/
                        3.7.1.- |
                                |
                         ExPASy |
                                |
                                v
          Succinic semialdehyde + 2,5-Dihydroxypyridine
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2-Hydroxy 3 or 5-aldo/keto pyridine derivative -----> 2-Hydroxypyridine derivative + Carboxylate (bt0153)
2- or 3-Hydroxypyridine -----> 2,5-Dihydroxypyridine (bt0362)
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Page Author(s): Michael Turnbull
December 27, 2007 Contact Us

This is the EAWAG-BBD reaction, reacID# r1442.
It was generated on December 13, 2025 at 8:29:00 PM CST. 

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