From Caffeine to Theophylline

Graphic of the reaction.

Reference
Hakil, M., Denis, S., Viniegra-Gonzalez, G., & Augur, C. (1998). Degradation and Product Analysis of Filamentous Fungi. Enzyme and Microbial Technology, 22(5), 355-359.

Search Medline for theophylline AND caffeine AND fungi.
35 citations on March 09, 2012. 
          Caffeine           
              |
              |  NAD(P)H + H+ + O2
     caffeine | /
  demethylase |/
    1.13.12.- | Search GenBank, 2 hits on Apr. 03, 2012
              |\
       ExPASy | \
              |  NAD(P)+ + H2O + CH2O
              v
        Theophylline
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
tertiary Amine -----> secondary Amine + Aldehyde or Ketone (bt0063)
[Caffeine (fungal)] [BBD Main Menu]

Page Author(s): Rachael Long
November 29, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1324.
It was generated on April 17, 2026 at 1:11:54 AM CDT. 

© 2026, EAWAG.