Rule bt0063

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Pattern 3938        All patterns
primary Amine -> Aldehyde or Ketone
secondary Amine -> Amine + Aldehyde or Ketone
tertiary Amine -> secondary Amine + Aldehyde or Ketone
Methylammonium derivative -> Trimethylamine + Aldehyde or Ketone


Aerobic Likelihood:              Likely

EAWAG-BBD Reaction(s):
2-(2-Aminoethoxy)acetate -----> Diglycolate (reacID# r1533)
6-Aminohexanoate -----> 6-Oxohexanoate (reacID# r0449)
Caffeine -----> Theophylline (reacID# r1324)
Cyclohexylamine -----> Cyclohexanone (reacID# r0754)
2,6-Diethyl-N-(methoxymethyl)aniline -----> Formaldehyde + 2,6-Diethylaniline (reacID# r1700)
Diethylamine -----> Acetaldehyde + Ethyl amine (reacID# r1589)
Dimethylamine -----> Methylamine + Formaldehyde (reacID# r1380)
Ethyl amine -----> Acetaldehyde (reacID# r1590)
Glyphosate -----> Aminomethylphosphonic acid (AMPA) + Glyoxylate (reacID# r0073)
Hexadecyltrimethylammonium chloride -----> Trimethylamine + Hexadecanal (reacID# r1373)
(R)-6-Hydroxynicotine -----> 6-Hydroxypseudooxynicotine (reacID# r0478)
(S)-6-Hydroxynicotine -----> 6-Hydroxypseudooxynicotine (reacID# r0477)
6-Hydroxypseudooxynicotine -----> 6-Hydroxy-3-succinoylpyridine (reacID# r1441)
Iminodiacetate -----> Glyoxylate + Glycine (reacID# r0589)
Methylamine -----> Formaldehyde (reacID# r0075)
4-Methylaminobutyrate -----> Formaldehyde + 4-aminobutanoate (reacID# r1827)
N-Methylmorpholine -----> Formaldehyde + Morpholine (reacID# r1570)
N-Methyltaurine -----> Methylamine + Sulfoacetaldehyde (reacID# r1565)
7-Methylxanthine -----> Xanthine (reacID# r1249)
Morpholine -----> 2-(2-Aminoethoxy)acetaldehyde (reacID# r1530)
Nitrilotriacetate -----> Glyoxylate + Iminodiacetate (reacID# r0587)
Nitrilotriacetate -----> Glyoxylate + Iminodiacetate (reacID# r0588)
3-Nitrotyramine -----> 4-Hydroxy-3-nitrophenylacetaldehyde (reacID# r1579)
3-Nitrotyrosine -----> 4-Hydroxy-3-nitrophenylpyruvate (reacID# r1598)
Nortropine -----> 6-Hydroxycyclohepta-1,4-dione (reacID# r1741)
Paraxanthine -----> 1-Methylxanthine (reacID# r1320)
Pyridoxamine -----> Pyridoxal (reacID# r1479)
Theobromine -----> 3-Methylxanthine (reacID# r1319)
Trimethylamine -----> Formaldehyde + Dimethylamine (reacID# r1378)
Trimethylamine N-oxide -----> Formaldehyde + Dimethylamine (reacID# r1409)
Tropine -----> Formaldehyde + Nortropine (reacID# r1740)
L-Tyrosine -----> 4-Hydroxyphenylpyruvate (reacID# r0297)

Comments:
Oxidative removal of an R group from an amine. An aldehyde is produced if the leaving R group is attached through a primary carbon. A ketone is produced if the leaving R group is attached through a secondary carbon. Rule will produce cis products in rings with double bonds.


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Page Author(s): Bo Kyeng Hou, Rachael Long, Michael Turnbull and Jiun-guo Yu
June 02, 2009

This is the EAWAG-BBD biotransformation rule, ruleID# bt0063.
It was generated on September 19, 2017 6:30:55 AM CDT.

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