From 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione to 3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

Graphic of the reaction.

Medline reference

Horinouchi M, Hayashi T, Kudo T. J Steroid Biochem Mol Biol (2004) 92(3): 143-54.

Search Medline for 3-HSA hydroxylase.

2 citations on March 09, 2012.

    3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione     
                                |
                                |  NADPH + H+ + O2
                          3-HSA | /
                    hydroxylase |/
                     1.14.14.12 | Search GenBank, 5 hits on Jun. 20, 2012
                          Kyoto |\
                         ExPASy | \
                                |  NADP+ + H2O
                                v
  3,4-Dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione   

EAWAG-BBD Biotransformation rules in accord with this reaction:

1-Hydroxy-2-unsubstituted aromatic -----> 1,2-Dihydroxyaromatic (bt0014)

Page Author(s): Andrew Rabins
April 22, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1150.
It was generated on March 22, 2025 at 8:49:34 PM CDT.

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