From 5-Hydroxyadamantan-2-one to 1-Hydroxy-4-oxahomoadamantan-5-one

Graphic of the reaction.

Medline reference
Selifonov SA. Biochem Biophys Res Commun (1992) 186(3): 1429-36.

Search Medline for Adamantanone AND oxidation.
12 citations on March 09, 2012. 
         5-Hydroxyadamantan-2-one          
                     |
                     |  NADH + H+ + O2
  2,5-diketocamphane | /
   1,2-monooxygenase |/
         1.14.13.162 |
               Kyoto |\
              ExPASy | \
                     |  NAD+ + H2O
                     v
    1-Hydroxy-4-oxahomoadamantan-5-one
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
cyclic Ketone -----> cyclic Ester (bt0071)
[Adamantanone] [BBD Main Menu]

Page Author(s): Jenny Kang
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0682.
It was generated on November 16, 2025 at 4:10:19 PM CST. 

© 2025, EAWAG.