From 4-Hydroxyphenylacetate to 3,4-Dihydroxyphenylacetate

Graphic of the reaction.

Medline reference
Arunachalam U, Massey V, Miller SM. J Biol Chem (1994) 269(1): 150-5.

Search Medline for 4-hydroxyphenylacetate 3-hydroxylase.
15 citations on July 26, 2012. 
              4-Hydroxyphenylacetate               
                         |
                         |  FADH2 + O2
  4-hydroxyphenylacetate | /
           3-hydroxylase |/
               1.14.14.9 | Search GenBank, 355 hits on Apr. 03, 2012
                   Kyoto |\
                  ExPASy | \
                         |  FAD+ + H2O
                         v
            3,4-Dihydroxyphenylacetate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Hydroxy-2-unsubstituted aromatic -----> 1,2-Dihydroxyaromatic (bt0014)
[Tyrosine] [BBD Main Menu]

Page Author(s): Michelle Wagner and Colin L. Sweeney
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0301.
It was generated on November 14, 2025 at 3:02:44 AM CST. 

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