From 4-Hydroxyphenylpyruvate to Homogentisate

Graphic of the reaction.

Medline reference
Ruetschi U, Odelhog B, Lindstedt S, Barros-Soderling J, Persson B, Jornvall H. Eur J Biochem (1992) 205(2): 459-66.

Search Medline titles for bacterial 4-hydroxyphenylpyruvate dioxygenase.
21 citations on March 09, 2012. 
               4-Hydroxyphenylpyruvate               
                          |
                          |  O2
  4-hydroxyphenylpyruvate | /
              dioxygenase |/
               1.13.11.27 | Search GenBank, 2520 hits on Apr. 03, 2012
                    Kyoto |\
                   ExPASy | \
                          |  CO2
                          v
                    Homogentisate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
2-Ketocarboxylate -----> Carboxylate + CO2 (bt0082)
2,5-unsubstituted 4-Hydroxyphenylacetate derivative -----> 2,5-Dihydroxyphenylacetate derivative (bt0234)
[Tyrosine] [BBD Main Menu]

Page Author(s): Colin L. Sweeney
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0298.
It was generated on February 6, 2026 6:37:59 PM CST. 

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