From Cyclohexanone to 1-Oxa-2-oxocycloheptane

Graphic of the reaction.

Graphic of its mechanism.

Medline reference
Trudgill PW. Methods Enzymol (1990) 188: 70-7.

Search Medline titles for cyclohexanone monooxygenase.
18 citations on June 21, 2012. 
              Cyclohexanone              
                    |
                    |  NADPH + O2
      cyclohexanone | /
  1,2-monooxygenase |/
         1.14.13.22 | Search GenBank, 30 hits on Apr. 03, 2012
              Kyoto |\
             ExPASy | \
                    |  NADP+ + OH-
                    v
         1-Oxa-2-oxocycloheptane
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
cyclic Ketone -----> cyclic Ester (bt0071)
[Cyclohexane] [BBD Main Menu]

Page Author(s): Michelle Wagner and Jian Ma
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0166.
It was generated on December 15, 2025 at 9:14:19 PM CST. 

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