From Isoniazid to Isonicotinate

Graphic of the reaction.

Medline reference
Gupta RC, Shukla OP. Indian J Exp Biol (1978) 16(10): 1047-51.

Search Medline for isonicotinic acid AND hydrolysis.
76 citations on March 09, 2012. 
                          Isoniazid                          
                              |
                              |  H2O
  isonicotinic acid hydrazide | /
                    hydrolase |/
                      3.5.1.- |
                              |\
                       ExPASy | \
                              |  Hydrazine
                              v
                        Isonicotinate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Lactam -----> Aminecarboxylate (bt0067)
[Isoniazid] [BBD Main Menu]

Page Author(s): Edward LaBelle
December 29, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1336.
It was generated on July 15, 2026 at 8:18:46 PM CDT. 

© 2026, EAWAG.