From 7-Methylxanthine to Xanthine

Graphic of the reaction.

Reference
Asano, Y., Komeda, T., & Yamada, H. (1993). Microbial Production of Theobromine from Caffeine. Bioscience, biotechnology, and biochemistry, 57(8), 1286-1289.

Search Medline for xanthine AND demethylase AND bacteria.
7 citations on March 09, 2012. 
         7-Methylxanthine          
                 |
                 |  NAD(P)H + H+ + O2
  heteroxanthine | /
     demethylase |/
     1.14.13.128 |
           Kyoto |\
          ExPASy | \
                 |  NAD(P)+ + H2O + CH2O
                 v
             Xanthine
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
tertiary Amine -----> secondary Amine + Aldehyde or Ketone (bt0063)
[Caffeine] [Caffeine (fungal)] [BBD Main Menu]

Page Author(s): Stephan M. Cameron and Rachael Long
May 17, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1249.
It was generated on January 20, 2026 at 3:29:06 AM CST. 

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