From Tetrachloro-cis,cis-muconate to 2,3,5-Trichlorodienelactone

Graphic of the reaction.
Medline reference: Hammer A, Hildenbrand T, Hoier H, Ngai KL, Schlomann M, Stezowski JJ. J Mol Biol (1993) 232(1): 305-7.
Search Medline for chloromuconate cycloisomerase AND bacterial.: 20 citations on March 09, 2012.

   Tetrachloro-cis,cis-muconate    
                 |
                 |
  chloromuconate |
  cycloisomerase |
         5.5.1.7 | Search GenBank, 227 hits on Apr. 03, 2012
           Kyoto |\
          ExPASy | \
                 |  Cl^-
                 v
    2,3,5-Trichlorodienelactone

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: 3-Halo-cis,cis-muconate derivative -----> cis-4-Carboxymethylenebut-2-en-4-olide derivative (bt0206)

[Tetrachlorobenzene] [BBD Main Menu]

Page Author(s): Yan Zhang
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0802.
It was generated on November 7, 2025 at 4:20:11 PM CST.

© 2025, EAWAG.