From 2,3,5-Trichloromaleylacetic acid to 2,4-Dichloro-3-oxoadipate

Graphic of the reaction.

Medline reference

Tompkins FC Jr, Goldsmith RL. Am Ind Hyg Assoc J (1977) 38(8): 371-7.

Search Medline for maleylacetate reductase AND bacterial.

33 citations on March 09, 2012.

  2,3,5-Trichloromaleylacetic acid   
                  |
                  |  H+ + 2NAD(P)H
    maleylacetate | /
        reductase |/
         1.3.1.32 | Search GenBank, 225 hits on Apr. 03, 2012
            Kyoto |\
           ExPASy | \
                  |  Cl- + 2NAD(P)+
                  v
      2,4-Dichloro-3-oxoadipate      

EAWAG-BBD Biotransformation rules in accord with this reaction:

2-Halomaleylacetate -----> 3-Oxoadipate derivative (bt0149)

Page Author(s): Yan Zhang
February 10, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r0804.
It was generated on December 3, 2024 at 2:44:45 PM CST.

© 2024, EAWAG.