An excellent page. I would like to see more animated reactions
(particularly useful for those of use that think in images and
pictures). Although a fee is resonable, I would hesitiate strongly to
make students and/or teachers in academia to pay. Let industry foot
the bill.
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I know this would be hard to do, but it would be nice to indicate when
there is biochemical evidence that a gene that is hit in medline actually
catalyzes the reaction it is associated with. So many gene functions are
assigned with no direct evidence that the enzyme encoded by said gene actually
catalyzes that reaction suggested. Sometimes there is a loose association by
showing that the bacterium that has the gene catalyzes the reaction. But with
all the gene duplication out there, you can't presume that a gene cloned, though
similar to other enzymes with the similar activity, is actually the primary
enzyme catalyzing the reaction for the bug.
Another feature that would be nice would be to have a graphic of a
dendogram of the gene hits and their related sequences available as a link. You
could have a feature where users could send sequences to you to add to the fastA
file used to generate the dendogram to help keep it up to date.
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The database is wonderful, thank you.
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I use it for problem solving for environmental contamination
Suggestions for pathways to add: PESTICIDES
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great web page, with a lot of information and links, however, I
haven't looked at it recently.
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Would like to see some pathways involving various terminal
electron acceptors such as nitrate, iron, manganese, sulfate etc.,
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I want to thank you for the information you mailed
I have been concerned mainley to the surfactants(anionic, cationic, and
nonionic.
But I am satis fied to say that I find your work helpful to me.
Thank you
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Congratulations. Keep up with the good work.
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1. It would be nice to have good links to enzyme home pages when they exist
2. Also the enzymes should be linked to the protein data base
3. The anaerobic pathways of acetate and methane formation are not in good
shape.
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I have filled out the survey by marking my preferences. These distinctions are
somewhat artificial because my use is situational dependent. You have an
interesting and changing resource. Keep up the good work.
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Thanks for a great web-site! I use the UM-BBD a lot.
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I trust the UM-BBD to provide as robust information as possible and
I value the links to related resources, which can help me to check
possibilities.
I feel that the underpinning provided by your publication of known pathways can and should be extendable to novel compounds entered by users. Agreed, no guarantees can be given, but such an organised semi-predictive facility would be very valuable.
I believe that UM-BBD on CD-ROM could be useful, but it would require frequent updating and extension.
Very well done so far! Keep going!
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Thank you for your very useful database. The principle research subject of
our laboratory is the biodegradation of toxic compounds like BTEX,
biphenyles, morpholine and diuron. I have just one suggestion about a
pathway you can include: phenol.
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Thanks for your service/web site
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I've found this site a useful resource in a Microbial Physiology course
that I teach. The students are asked to choose a compound from a list that
I provide, and to report on the biodegradation pathway(s) associated with
that compound. The purpose is to show them that there are available
resources they can tap beyond the textbooks, and to illustrate the
diversity of metabolism. I've been surprised by how many students had not
been exposed to the web before (other than registering for classes).
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This is a great site. It should continue to be funded. It would be nice
to have an easy method of submitting comments concerning possible mistakes
or additions to the pathways, rxs, etc.
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I work on predicting and evaluating progress in biological remediation-projects
of
contaminated soil and groundwater, mostly of oil-products.
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The database is splendid, perhaps more attention could be paid to tighter
integration with other databases of the scientific literature and especially
patent literature.
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I contract reactor vessel volume bioremediation of hazardous wastes using
protocols developed by our company
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This is a valuable service for us. Keep it up!
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Page Author(s): Lynda Ellis
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