Rule bt0043

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Pattern 2033
2-Oxo-4-hydroxycarboxylate -> Aldehyde + Pyruvate


Aerobic Likelihood:              Neutral

EAWAG-BBD Reaction(s):
5-Chloro-4-hydroxy-2-oxopentanate -----> Chloroacetaldehyde + Pyruvate (reacID# r1437)
2,4-Dihydroxy-hept-trans-2-ene-1,7-dioate -----> Pyruvate + Succinic semialdehyde (reacID# r0370)
(2Z)-2,4-Dihydroxydec-2-enedioate -----> Pyruvate + 7-Oxoheptanoate (reacID# r1174)
4-Hydroxy-2-oxohexanoate -----> Pyruvate + Propanal (reacID# r0183)
4-Hydroxy-2-oxovalerate -----> Pyruvate + Acetaldehyde (reacID# r0100)

Comments:
Rule will produce cis products in rings with double bonds. This rule is part of the lower extradiol ring cleavage super rule.

Similarities:
bt0427: 3-Hydroxy-3-alkylcarboxylate --> Acetate + Ketone

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Page Author(s): Bo Kyeng Hou, Rachael Long, Michael Turnbull and Jiun-guo Yu
November 12, 2007

This is the EAWAG-BBD biotransformation rule, ruleID# bt0043.
It was generated on September 25, 2017 4:39:37 AM CDT.

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