From (2E,4E)-2-Hydroxyhexa-2,4-dienoate to 4-Hydroxy-2-oxohexanoate

Graphic of the reaction.

Medline reference
Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T. Appl Environ Microbiol (2005) 71(9): 5275-81.

Search Medline titles for testosterone AND metabolism AND bacteria.
29 citations on September 10, 2012.
            (2E,4E)-2-Hydroxyhexa-2,4-dienoate             
                             |
                             |  H2O
  2-hydroxyhexa-2,4-dienoate | /
                   hydratase |/
                   4.2.1.132 | Search GenBank, 12 hits on Oct. 11, 2012
                       Kyoto |
                      ExPASy |
                             |
                             v
                 4-Hydroxy-2-oxohexanoate                  
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Enol -----> Keto (bt0044)
1-Oxo 2- or 3-ene derivative -----> 1-Oxo-3-hydroxy derivative (bt0021)

[Testosterone] [BBD Main Menu]

Page Author(s): Carla Essenberg
July 26, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1281.
It was generated on July 20, 2019 10:48:07 AM CDT.

© 2019, EAWAG.