From 2-Chloro-N-isopropylacetanilide to 2-Chloro-N-isopropylacetamide and Catechol

Graphic of the reaction.

Medline reference
Villarreal DT, Turco RF, Konopka A. Appl Environ Microbiol (1991) 57(8): 2135-40.

Search Medline for propachlor AND bacteria AND degradation.
19 citations on March 09, 2012. 
                   2-Chloro-N-isopropylacetanilide                   
                                  |
                                  |  O2 + H+ + NADH
  2-chloro-N-isopropylacetanilide | /
                  1,2-dioxygenase |/
                        1.14.12.- |
                                  |\
                           ExPASy | \
                                  |  NAD+
                                  v
              2-Chloro-N-isopropylacetamide + Catechol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-Amino-2-unsubstituted aromatic -----> vic-Dihydroxyaromatic + Amine (bt0065)
[2-Chloro-N-isopropylacetanilide] [BBD Main Menu]

Page Author(s): Valerie Anne Edwards
August 14, 2005 Contact Us

This is the EAWAG-BBD reaction, reacID# r0724.
It was generated on July 9, 2025 at 3:42:40 AM CDT. 

© 2025, EAWAG.