The EAWAG-BBD Isoniazid Pathway

• Acetyl-CoA + Isoniazid -----> N-Acetylisoniazid (reacID# r1333)
• cis-Aconitamide -----> cis-Aconitate (reacID# r1344)
• Citrazinate -----> cis-Aconitamide (reacID# r1343)
• Citrazinate -----> Maleamate (reacID# r1342)
• Citrazinate -----> Succinic semialdehyde (reacID# r1345)
• Citrazinate -----> 2,3,6-Trihydroxyisonicotinate (reacID# r1339)
• 2-Hydroxyisonicotinate -----> Citrazinate (reacID# r1338)
• Isoniazid -----> Isonicotinamide (reacID# r1334)
• Isoniazid -----> Isonicotinate (reacID# r1336)
• Isoniazid -----> Pyridine-4-carboxaldehyde (reacID# r1335)
• Isonicotinamide -----> Isonicotinate (reacID# r1346)
• Isonicotinate -----> 2-Hydroxyisonicotinate (reacID# r1337)
• 2,3,6-Trihydroxyisonicotinate -----> 2,3,6-Trihydroxypyridine (reacID# r1340)
• 2,3,6-Trihydroxypyridine -----> Maleamate (reacID# r0483)

• Acetyl-CoA [72-89-9] (compID# c0031)
• N-Acetylisoniazid [1078-38-2] (compID# c1170)
• cis-Aconitamide [538314-83-9] (compID# c1168)
• cis-Aconitate [585-84-2] (compID# c1169)
• Citrazinate [99-11-6] (compID# c1166)
• 2-Hydroxyisonicotinate [22282-72-0] (compID# c1165)
• Isoniazid [54-85-3] (compID# c1161)
• Isonicotinamide [1453-82-3] (compID# c1173)
• Isonicotinate [55-22-1] (compID# c1164)
• Maleamate [557-24-4] (compID# c0476)
• Pyridine-4-carboxaldehyde [872-85-5] (compID# c1163)
• Succinic semialdehyde [692-29-5] (compID# c0311)
• 2,3,6-Trihydroxyisonicotinate (compID# c1167)
• 2,3,6-Trihydroxypyridine [39954-19-3] (compID# c0475)

• EC 1.11.1.6 catalase-peroxidase (enzymeID# e0834)
• EC 1.17.-.- 2-hydroxyisonicotinate dehydrogenase (enzymeID# e0836)
• EC 1.17.-.- citrazinate dehydrogenase (enzymeID# e0838)
• EC 1.17.-.- isonicotinate dehydrogenase (enzymeID# e0835)
• EC 2.3.1.5 arylamine N-acetyltransferase (enzymeID# e0341)
• EC 3.5.1.- cis-aconitamide amidase (enzymeID# e0840)
• EC 3.5.1.- isonicotinic acid hydrazide hydrolase (enzymeID# e0833)
• EC 3.5.1.4 amidase (enzymeID# e0068)
• EC 3.5.2.- citrazinate hydrolase (enzymeID# e0839)
• EC 4.1.1.- 2,3,6-trihydroxyisonicotinate decarboxylase (enzymeID# e0837)

Page Author(s): Edward LaBelle
Thu Nov 9 16:38:26 CST 2006 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Isoniazid Pathway.
It was generated on July 12, 2025 at 3:00:09 AM CDT.

© 2025, EAWAG.