From 2,3,6-Trihydroxypyridine to Maleamate

Graphic of the reaction.

Medline reference
Gherna RL, Richardson SH, Rittenberg SC. J Biol Chem (1965) 240(9): 3669-74.

Search Medline for 2,3,6-Trihydroxypyridine.
1 citations on August 08, 2012.
  2,3,6-Trihydroxypyridine   
              |
              |  O2
              | /
              |/
              |
              |\
              | \
              |  2H+
              v
[(2Z,4E)-4-(carboxylatoimino)-4-hydroxybut-2-enoate]
              |
              |  H+
              | /
              |/
              |
              |\
              | \
              |  CO2
              v
          Maleamate          
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-Dihydroxypyridine -----> intradiol ring cleavage (bt0254)
N-carboxylate Amide -----> Amide + CO2 (bt0280)

[Isoniazid] [Nicotine] [BBD Main Menu]

Page Author(s): Ben Vickers and Michael Turnbull
January 27, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r0483.
It was generated on September 26, 2017 12:39:21 AM CDT.

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