The EAWAG-BBD 4-Chlorobiphenyl Pathway

• 4-Chlorobiphenyl -----> cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl (reacID# r0133)
• cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl -----> 2,3-Dihydroxy-4'-chlorobiphenyl (reacID# r0134)
• 2,3-Dihydroxy-4'-chlorobiphenyl -----> 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate (reacID# r0135)
• 4-Hydroxy-2-oxovalerate -----> Pyruvate + Acetaldehyde (reacID# r0100)
• 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate -----> cis-2-Hydroxypenta-2,4-dienoate + 4-Chlorobenzoate (reacID# r0136)
• cis-2-Hydroxypenta-2,4-dienoate -----> 4-Hydroxy-2-oxovalerate (reacID# r0101)

• Acetaldehyde [75-07-0] (compID# c0160)
• 4-Chlorobenzoate [74-11-3] (compID# c0103)
• 4-Chlorobiphenyl [2051-62-9] (compID# c0177)
• cis-2,3-Dihydro-2,3-dihydroxy-4'-chlorobiphenyl [119386-12-8] (compID# c0178)
• 2,3-Dihydroxy-4'-chlorobiphenyl [119386-13-9] (compID# c0179)
• 4-Hydroxy-2-oxovalerate [3318-73-8] (compID# c0101)
• 2-Hydroxy-6-oxo-6-(4'-chlorophenyl)-hexa-2,4-dienoate (compID# c0180)
• cis-2-Hydroxypenta-2,4-dienoate [159694-16-3] (compID# c0102)
• Pyruvate [127-17-3] (compID# c0159)

• EC 1.3.1.56 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase (enzymeID# e0134)
• EC 1.13.11.39 2,3-dihydroxybiphenyl 1,2-dioxygenase (enzymeID# e0127)
• EC 1.14.12.18 biphenyl dioxygenase (enzymeID# e0089)
• EC 3.7.1.8 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (enzymeID# e0033)
• EC 4.1.3.39 4-hydroxy-2-oxovalerate aldolase (enzymeID# e0077)
• EC 4.2.1.80 2-oxopent-4-enoate hydratase (enzymeID# e0078)

Page Author(s): Shou-Lin Chang, Dong Jun Oh and John Haddock
December 15, 1997 4:39:12 PM CST Contact Us

This is the EAWAG-BBD compounds and reactions page for the 4-Chlorobiphenyl Pathway.
It was generated on April 23, 2024 at 9:54:08 AM CDT.

© 2024, EAWAG.