Hypophosphite Pathway Map

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This pathway was completed by Sean Anderson and John Schrom, University of Minnesota.

Reduced phosphorous compounds are produced on a large scale, however metabolism of these compounds is relatively unexplored. Many microorganisms like Escherichia coli, Pseudomonas fluorescens, and Klebsiella aerogenes, are known to oxidize two important reduced phosphorous compounds: phosphite and hypophosphite. White and Metcalf (2002) have shown that, in Pseudomonas stutzeri WM88, hypophosphite oxidation takes place via a phosphite intermediate.

The following is a text-format Hypophosphite pathway map. An organism which can initiate the pathway is given, but other organisms may also carry out later steps. Follow the links for more information on compounds or reactions. This map is also available in graphic (4k) format.

                                        Hypophosphite
                                  Pseudomonas stutzeri WM88
                                              |
                                              |
                                              | hypophosphite dioxygenase
                                              |
                                              |
                                              v 
                                          Phosphite
                                              |
                                              |
                                              | phosphite dehydrogenase
                                              |
                                              |
                                              v 
                                          Phosphate

[Compounds and Reactions] [BBD Main Menu]

Page Author: Sean Anderson and John Schrom

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