1-Aminocyclopropane-1-carboxylate Pathway Map

1-Aminocyclopropane-1-carboxylate (ACP) is a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene, a fruit-ripening hormone in plants. Overripening of fruits may cause economic implications. Control of ethylene biosynthesis may delay this.

It has been found that several microorganisms such as the bacterium Pseudomonas sp. ACP and the yeast Williopsis saturnus contain ACP deaminase and degrade ACP to 2-oxobutanoate and ammonia (Walsh et al., 1981). This may be a way to reduce ethylene synthesis and delay fruit ripening.

The following is a text-format 1-Aminocyclopropane-1-carboxylate pathway map. Organisms which can initiate the pathway are given, but other organisms may also carry out later steps. Follow the links for more information on compounds or reactions. This map is also available in graphic (8k) format.

 


     1-Aminocyclopropane-1-carboxylate                 
            Pseudomonas sp. ACP
            Williopsis saturnus    
                     |
                     |
                     | 1-aminocyclopropane-
                     | 1-carboxylate deaminase
                     | 
                     |
                     v                      Methionine and            
              2-Oxobutanoate <----from the Threonine Pathway      
                     |
                     |
                     | 2-oxobutyrate synthase
                     | 
                     |
                     v                               
               Propanoyl-CoA      
                     |
                     |
                     |
                     |
                     |
                     v
                Intermediary 
                 Metabolism
                   (KEGG)

Page Author(s): Aidan Peterson and Zhifu Sun

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