UM-BBD Biotransformation Rule Subset A

• _____ Acetophenone derivative -----> Benzoyl acetate derivative (bt0202)
  
• _____ Acid chloride -----> Carboxylate (bt0026)
  
• _____ Adamantanonoid -----> 4-Oxahomoadamantan-5-one derivative (bt0135)
  
• _____ 5-unsubstituted Adamantanonoid -----> 5-Hydroxyadamantan-2-one derivative (bt0134)
  
• _____ primary Alcohol -----> Aldehyde (bt0001)
  
• _____ secondary Alcohol -----> Ketone (bt0002)
  
• _____ Aldehyde -----> Carboxylate (bt0003)
  
• _____ 1-Aldo/keto-2-ene -----> Carboxylate + 1-ene (bt0040)
  
• _____ Aldoxime -----> Nitrile (bt0062)
  
• _____ secondary Aliphatic -----> secondary Alcohol (bt0242)
  
• _____ tertiary Aliphatic -----> tertiary Alcohol (bt0241)
  
• _____ Alkene -----> Alcohol (bt0021)
  
• _____ Alkene -----> Alkane (bt0291)
  
• _____ 1,2-Alkene -----> 1,2-Epoxide (bt0049)
  
• _____ Alkyl sulfate -----> Alkyl 1-ol (bt0143)
  
• _____ Alkyl-2-ene-CoA -----> 2-Hydroxyalkyl-CoA (bt0185)
  
• _____ Alkyl-CoA derivative -----> Alkyl phosphate derivative (bt0203)
  
• _____ 2,3-unsubstituted-Alkyl-CoA derivative -----> 2,3-Didehydroalkyl-CoA derivative (bt0180)
  
• _____ Alkylphosphonic acid -----> R-CH₃ + Phosphate (bt0147)
  
• _____ Alkylsulfonate -----> R-OH + HSO₃^- (bt0227)
  
• _____ Alkylsulfonic acid derivative -----> Aldehyde + Sulfurous acid (bt0286)
  
• _____ Alkyne -----> Alkene (bt0070)
  
• _____ terminal Alkyne -----> Aldehyde (bt0020)
  
• _____ N, N-disubstituted Amide -----> N-alkyl Amide + aldehyde or ketone (bt0293)
  
• _____ N-alkyl Amide -----> Amide + aldehyde or ketone (bt0293)
  
• _____ cyclic secondary Amine -----> Aminoalcohol (bt0294)
  
• _____ primary Amide -----> Carboxylate + NH₃ (bt0027)
  
• _____ secondary Amide -----> Carboxylate + primary Amine (bt0025)
  
• _____ tertiary Amide -----> Carboxylate + secondary Amine (bt0067)
  
• _____ alkyl Amine -----> Aldehyde or Ketone (bt0076)
  
• _____ secondary Amine -----> primary Alcohol + primary Amine (bt0061)
  
• _____ secondary Amine -----> Amine + Aldehyde or Ketone (bt0063)
  
• _____ tertiary Amine -----> secondary Amine + Aldehyde or Ketone (bt0063)
  
• _____ 1-Amino-2-hydroxy-3-unsubstituted benzenoid -----> distal extradiol ring cleavage (bt0041)
  
• _____ 1-Amino-2-unsubstituted benzenoid -----> 1,2-Dihydroxybenzenoid (bt0065)
  
• _____ 2-Amino-3-hydroxycarboxylate -----> 2-Ketocarboxylate (bt0137)
  
• _____ cis-4-Amino-6-carboxy-2-oxo-hexa-3,5-dienoate derivative -----> trans-4-Amino-6-carboxy-2-oxo-hexa-3,5-dienoate derivative (bt0289)
  
• _____ Aminobenzenoid derivative + Acetyl-CoA -----> Acetamidobenzenoid derivative + CoASH (bt0207)
  
• _____ 2-Aminobenzoyl-CoA derivative -----> Benzoyl-CoA derivative (bt0199)
  
• _____ 5-unsubstituted 2-Aminobenzoyl-CoA derivative -----> 2-Amino-5-oxo-cyclohex-1-enecarboxy-CoA derivative (bt0212)
  
• _____ 1-Aminocyclopropane-1-carboxylate derivative -----> 2-Oxobutanoate derivative (bt0145)
  
• _____ 4-Aminophenol derivative -----> 4-Benzoquinone monoimine derivative (bt0105)
  
• _____ Aromatic ketone side chain -----> Aromatic ring(s) + Carboxylate (bt0153)
  
• _____ polynuclear Aromatic system -----> Hemiacetal-like polynuclear aromatic system (bt0196)
  
• _____ Aryl isocyanate -----> Aryl carbamate (bt0110)
  
• _____ Aryl phosphate -----> Phenol derivative + Phosphate derivative (bt0104)
  
• _____ Aryl thiophosphate -----> Phenol derivative + Thiophosphate derivative (bt0102)
  
• _____ vic-unsubstituted Benzenoid -----> cis-Dihydroxydihydrobenzenoid (bt0005)
  
• _____ monosubstituted Benzenoid -----> Add m-OH (bt0012)
  
• _____ monosubstituted Benzenoid -----> Add o-OH (bt0011)
  

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