From Cocaine to Benzoate and Ecgonine methyl ester

Graphic of the reaction.

Medline reference
Bresler MM, Rosser SJ, Basran A, Bruce NC. Appl Environ Microbiol (2000) 66(3): 904-8.

Search Medline titles for cocaine esterase AND bacteria.
15 citations on September 27, 2012. 
               Cocaine               
                  |
                  |  H2O
          cocaine | /
         esterase |/
         3.1.1.84 | Search GenBank, 54 hits on Apr. 03, 2012
            Kyoto |
           ExPASy |
                  |
                  v
  Benzoate + Ecgonine methyl ester
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Ester -----> Alcohol + Carboxylate (bt0024)
[Cocaine] [BBD Main Menu]

Page Author(s): Jeffrey P. Osborne
November 10, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1798.
It was generated on February 18, 2026 2:28:44 PM CST. 

© 2026, EAWAG.