From 3-Phenoxybenzoate to Phenol and 3,4-Dihydroxybenzoate

Graphic of the reaction.

Reference
Wittich R-M, Schmidt S, Fortnagel P. FEMS Microbiology Letters, (1990) 67:157-160.

Search Medline for 3-phenoxybenzoate biodegradation.
4 citations on May 09, 2012. 
          3-Phenoxybenzoate          
                  |
                  |  NADH + H+ + O2
  phenoxybenzoate | /
  1,2-dioxygenase |/
        1.14.12.- | Search GenBank, 89 hits on Apr. 21, 2012
                  |\
           ExPASy | \
                  |  NAD+
                  v
 [2,3-Dihydrodiol-3-Phenoxybenzoate] 
                  |
                  |
                  |
                  |
                  |
                  |
                  |
                  v
   Phenol + 3,4-Dihydroxybenzoate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
polynuclear Aromatic system -----> 1,2-dioxygenation and cleavage at connecting atom (bt0374)
[Permethrin] [BBD Main Menu]

Page Author(s): Jeffrey P. Osborne
October 23, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1768.
It was generated on January 24, 2026 3:37:19 PM CST. 

© 2026, EAWAG.