From Isobutylcatechol to 5-Formyl-2-hydroxy-7-methyl-octa-2,4-dienoate

Graphic of the reaction.
Medline reference: Kagle J, Porter AW, Murdoch RW, Rivera-Cancel G, Hay AG. Adv Appl Microbiol (2009) 67: 65-108.
Search Medline for ibuprofen bacterial metabolism.: 19 citations on March 09, 2012.

                 Isobutylcatechol                 
                         |
                         |  O₂
        isobutylcatechol | /
         2,3-dioxygenase |/
               1.13.11.- |
                         |\
                  ExPASy | \
                         |  H⁺
                         v
  5-Formyl-2-hydroxy-7-methyl-octa-2,4-dienoate

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)

[Ibuprofen] [BBD Main Menu]

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July 15, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1737.
It was generated on March 11, 2026 at 8:47:29 AM CDT.

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