From Bisphenol A to Hydroquinone and 4-(2-Hydroxypropan-2-yl)phenol

Graphic of the reaction.

Medline reference
Gabriel FL, Cyris M, Giger W, Kohler HP. Chem Biodivers (2007) 4(9): 2123-37.

Search Medline for Bisphenol A ipso substitution.
4 citations on March 09, 2012. 
                   Bisphenol A                    
                         |
                         |  O2 + NADPH + 2H+
              bisphenolA | /
         1-monooxygenase |/
                1.14.-.- |
                         |\
                  ExPASy | \
                         |  H2O + NADP+
                         v
      [2-(4-Hydroxyphenyl)-isopropyl cation]      
                         |
                         |  H2O
                         | /
                         |/
                         |
                         |\
                         | \
                         |  H+
                         v
  Hydroquinone + 4-(2-Hydroxypropan-2-yl)phenol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
4-substituted Phenol -----> Hydroquinone + primary Alcohol (bt0436)
[Bisphenol A] [BBD Main Menu]

Page Author(s): Lynda Ellis and Shawn Balcome
May 03, 2011 Contact Us

This is the EAWAG-BBD reaction, reacID# r1724.
It was generated on January 17, 2026 at 1:57:42 PM CST. 

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