From Saccharin to Catechol

Graphic of the reaction.

Medline reference
Schleheck D, Cook AM. Arch Microbiol (2003) 179(3): 191-6.

Search Medline for saccharin dioxygenase.
2 citations on March 09, 2012. 
          Saccharin          
              |
              |  NADH + O2 + H+
    saccharin | /
  dioxygenase |/
    1.14.12.- |
              |\
       ExPASy | \
              |  NAD+
              v
[3,7-dihydroxydihydro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide]
              |
              |  3H+ + 3[O]
              | /
              |/
              |
              |\
              | \
              |  CO2 + SO42- + NH4+
              v
          Catechol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
Saccharin -----> Catechol (bt0425)
[Benzoate] [BBD Main Menu]

Page Author(s): Sujana Mittapalli
July 15, 2010 Contact Us

This is the EAWAG-BBD reaction, reacID# r1667.
It was generated on April 13, 2026 at 9:41:09 AM CDT. 

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