From 4,5-Dimethylcatechol to 2-Hydroxy-4,5-dimethyl-6-oxohexa-2,4-dienoate

Graphic of the reaction.

Medline reference

Jang JY, Kim D, Bae HW, Choi KY, Chae JC, Zylstra GJ, Kim YM, Kim E. J Microbiol (2005) 43(4): 325-30.

Search Medline for o-xylene meta-cleavage.

11 citations on March 09, 2012.

               4,5-Dimethylcatechol               
                         |
                         |  O2
    4,5-dimethylcatechol | /
         2,3-dioxygenase |/
               1.13.11.- |
                         |\
                  ExPASy | \
                         |  H+
                         v
  2-Hydroxy-4,5-dimethyl-6-oxohexa-2,4-dienoate   

EAWAG-BBD Biotransformation rules in accord with this reaction:

vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)

Page Author(s): Michael Turnbull
January 05, 2009 Contact Us

This is the EAWAG-BBD reaction, reacID# r1558.
It was generated on November 16, 2025 at 10:10:07 AM CST.

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