From o-Xylene to 4,5-Dimethylcatechol

Graphic of the reaction.

Medline reference
Jang JY, Kim D, Bae HW, Choi KY, Chae JC, Zylstra GJ, Kim YM, Kim E. J Microbiol (2005) 43(4): 325-30.

Search Medline for o-xylene meta-cleavage.
11 citations on March 09, 2012. 
              o-Xylene               
                  |
                  |  O2 + 2e- + 2H+
         o-xylene | /
  4,5-dioxygenase |/
         1.14.-.- |
                  |
           ExPASy |
                  |
                  v
[4,5-Dimethylcyclohexa-3,5-diene-1,2-diol]
                  |
                  |
                  |
                  |
                  |\
                  | \
                  |  2e- + 2H+
                  v
        4,5-Dimethylcatechol
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
vic-unsubstituted Aromatic -----> vic-Dihydroxyaromatic (bt0005)
[o-Xylene] [BBD Main Menu]

Page Author(s): Michael Turnbull
January 05, 2009 Contact Us

This is the EAWAG-BBD reaction, reacID# r1557.
It was generated on November 14, 2025 at 3:45:08 PM CST. 

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