From 3-Hydroxy-2-methylpyridine-5-carboxylate to 2-(Acetamidomethylene)succinate

Graphic of the reaction.

Medline reference
Nelson MJ, Snell EE. J Biol Chem (1986) 261(32): 15115-20.

Search Medline for 1.14.12.4.
15 citations on March 09, 2012. 
                           3-Hydroxy-2-methylpyridine-5-carboxylate                            
                                               |
                                               |  O2 + H+ + NADH
  2-methyl-3-hydroxypyridine-5-carboxylic acid | /
                                     oxygenase |/
                                     1.14.12.4 | Search GenBank, 5 hits on Apr. 03, 2012
                                         Kyoto |\
                                        ExPASy | \
                                               |  NAD+
                                               v
                                2-(Acetamidomethylene)succinate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
3-Hydroxy-2-methylpyridine-5-carboxylate derivative -----> 2-(Acetamidomethylene)succinate derivative (bt0377)
[Pyridoxine] [BBD Main Menu]

Page Author(s): Erik Reynolds
May 05, 2008 Contact Us

This is the EAWAG-BBD reaction, reacID# r1523.
It was generated on November 11, 2025 at 4:49:42 PM CST. 

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