From 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate to 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate

Graphic of the reaction.
Medline reference: Nelson MJ, Snell EE. J Biol Chem (1986) 261(32): 15115-20.
Search Medline for 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate.: 2 citations on March 09, 2012.

                            2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate                            
                                                    |
                                                    |  H⁺+ NADH + O₂
  2-methyl-3-hydroxy-5-formylpyridine-4-carboxylate | /
                                      dehydrogenase |/
                                            1.2.1.- |
                                                    |\
                                             ExPASy | \
                                                    |  NAD⁺+ H₂O
                                                    v
                              3-Hydroxy-2-methylpyridine-4,5-dicarboxylate

Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:: Aldehyde -----> Carboxylate (bt0003)

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Page Author(s): Erik Reynolds
May 05, 2008 Contact Us

This is the EAWAG-BBD reaction, reacID# r1521.
It was generated on April 2, 2025 at 2:49:13 PM CDT.

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