From Diphenyl ether to 2,3-Dihydroxydiphenyl ether

Graphic of the reaction.

Medline reference
Kim YM, Nam IH, Murugesan K, Schmidt S, Crowley DE, Chang YS. Appl Microbiol Biotechnol (2007) 77(1): 187-94.

Search Medline for diethyl ether 2,3-dioxygenase.
2 citations on September 13, 2012. 
           Diphenyl ether            
                  |
                  |  O2 + NADH + H+
   diphenyl ether | /
  2,3-dioxygenase |/
        1.14.12.- |
                  |\
           ExPASy | \
                  |  NAD+
                  v
[2,3-Dihydrodihydroxydiphenyl ether] 
                  |
                  |  NAD+
                  | /
                  |/
                  |
                  |\
                  | \
                  |  NADH + H+
                  v
     2,3-Dihydroxydiphenyl ether
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
mono-carbon-substituted Benzenoid -----> 1-substituted-2,3-dihydroxy Benzenoid (bt0353)
[Phenol Family ] [BBD Main Menu]

Page Author(s): Lynda Ellis and Michael Turnbull
March 11, 2008 Contact Us

This is the EAWAG-BBD reaction, reacID# r1450.
It was generated on March 11, 2026 at 8:40:58 AM CDT. 

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