From Isonicotinate to 2-Hydroxyisonicotinate

Graphic of the reaction.

Medline reference
Kretzer A, Frunzke K, Andreesen JR. J Gen Microbiol (1993) 139(11): 2763-72.

Search Medline titles for Isoniazid metabolism AND bacteria.
12 citations on September 11, 2012. 
          Isonicotinate          
                |
                |  acceptor + H2O
  isonicotinate | /
  dehydrogenase |/
       1.17.-.- |
                |\
         ExPASy | \
                |  reduced acceptor
                v
     2-Hydroxyisonicotinate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
substituted Pyridine -----> Add m-OH (bt0012)
[Isoniazid] [BBD Main Menu]

Page Author(s): Edward LaBelle
December 29, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1337.
It was generated on November 7, 2025 at 3:35:55 PM CST. 

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