From 1-Methylxanthine to Xanthine

Graphic of the reaction.

Reference
Asano, Y., Komeda, T., & Yamada, H. (1993). Microbial Production of Theobromine from Caffeine. Bioscience, biotechnology, and biochemistry, 57(8), 1286-1289.

Search Medline for Microorganisms AND caffeine AND catabolism.
16 citations on March 09, 2012. 
         1-Methylxanthine          
                 |
                 |  NAD(P)H + H+ + O2
  heteroxanthine | /
     demethylase |/
     1.14.13.128 |
           Kyoto |\
          ExPASy | \
                 |  NAD(P)+ + H2O + CH2O
                 v
             Xanthine
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
N-substituted Amide -----> Amide + Aldehyde or Ketone (bt0243)
[Caffeine (fungal)] [BBD Main Menu]

Page Author(s): Rachael Long
November 30, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1331.
It was generated on December 15, 2025 at 8:20:22 PM CST. 

© 2025, EAWAG.