From Theophylline to 1-Methylxanthine

Graphic of the reaction.

Reference
Hakil, M., Denis, S., Viniegra-Gonzalez, G., & Augur, C. (1998). Degradation and Product Analysis of Filamentous Fungi. Enzyme and Microbial Technology, 22(5), 355-359.

Search Medline for theophylline AND fungus AND caffeine.
27 citations on March 09, 2012. 
         Theophylline          
               |
               |  NAD(P)H + H+ + O2
  theophylline | /
   demethylase |/
     1.13.12.- |
               |\
        ExPASy | \
               |  NAD(P)+ + H2O + CH2O
               v
       1-Methylxanthine
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
N-substituted Amide -----> Amide + Aldehyde or Ketone (bt0243)
[Caffeine (fungal)] [BBD Main Menu]

Page Author(s): Rachael Long
November 29, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1327.
It was generated on January 18, 2026 at 7:20:02 PM CST. 

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