From 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate to 4-Fluorocatechol

Graphic of the reaction.

Medline reference

Schreiber A, Hellwig M, Dorn E, Reineke W, Knackmuss HJ. Appl Environ Microbiol (1980) 39(1): 58-67.

Search Medline for cis-diol+dehydrogenase.

6 citations on September 06, 2012.

  5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate   
                             |
                             |  NAD+
                    cis-diol | /
               dehydrogenase |/
                    1.3.1.25 | Search GenBank, 31 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  NADH + CO2
                             v
                     4-Fluorocatechol                     

EAWAG-BBD Biotransformation rules in accord with this reaction:

1-Carboxy-1,2-dihydroxy-2-hydrobenzenoid -----> Catechol derivative (bt0056)

Page Author(s): Maria Stewart
May 11, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1221.
It was generated on December 13, 2025 at 8:02:02 PM CST.

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