From 3-Fluorobenzoate to 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate

Graphic of the reaction.

Medline reference
Yamaguchi M, Fujisawa H. J Biol Chem (1980) 255(11): 5058-63.

Search Medline for 3-fluorobenzoate.
24 citations on March 09, 2012. 
                     3-Fluorobenzoate                     
                             |
                             |  NADH + H+ + O2
                    benzoate | /
             1,2-dioxygenase |/
                  1.14.12.10 | Search GenBank, 17 hits on Apr. 03, 2012
                       Kyoto |\
                      ExPASy | \
                             |  NAD+
                             v
  5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate
Display a pathway starting from this reaction.

EAWAG-BBD Biotransformation rules in accord with this reaction:
1-carboxy-2-unsubstituted Aromatic -----> 1-Carboxy-1,2-dihydroxy-2-hydroaromatic (bt0368)
[3-Fluorobenzoate] [BBD Main Menu]

Page Author(s): Maria Stewart
May 11, 2006 Contact Us

This is the EAWAG-BBD reaction, reacID# r1218.
It was generated on November 12, 2025 at 1:43:12 PM CST. 

© 2025, EAWAG.